Details for gene set NCI_SIGNALING BY AURORA KINASES[GSEA]

Table: GSEA Results Summary

Dataset	set03_wtNotch_versus_truncNotch
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	NCI_SIGNALING BY AURORA KINASES
Enrichment Score (ES)	0.49292588
Normalized Enrichment Score (NES)	2.1530337
Nominal p-value	0.0
FDR q-value	0.0050067655
FWER p-Value	0.027

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SMC2	11	5.050	0.0411	Yes
2	NDC80	138	3.521	0.0634	Yes
3	RIPK2	243	3.252	0.0846	Yes
4	BIRC2	245	3.248	0.1114	Yes
5	MDM2	259	3.228	0.1373	Yes
6	NCAPH	260	3.228	0.1640	Yes
7	TPX2	474	2.908	0.1765	Yes
8	RASA1	476	2.908	0.2005	Yes
9	CHUK	639	2.746	0.2144	Yes
10	NDEL1	670	2.716	0.2352	Yes
11	CUL3	707	2.691	0.2555	Yes
12	PSMA3	751	2.659	0.2751	Yes
13	TRAF6	790	2.620	0.2947	Yes
14	MALT1	926	2.531	0.3083	Yes
15	IKBKG	991	2.489	0.3254	Yes
16	NCL	1029	2.462	0.3437	Yes
17	KIF23	1105	2.417	0.3596	Yes
18	CYLD	1408	2.236	0.3618	Yes
19	UBE2D3	1526	2.167	0.3734	Yes
20	NSUN2	1710	2.069	0.3806	Yes
21	PIK3CA	1784	2.033	0.3934	Yes
22	BCL3	1957	1.936	0.4001	Yes
23	SGOL1	2019	1.909	0.4126	Yes
24	NOD2	2179	1.826	0.4191	Yes
25	IKBKB	2579	1.645	0.4112	Yes
26	SMC4	2617	1.626	0.4226	Yes
27	REL	3030	1.441	0.4122	Yes
28	MAPK14	3104	1.409	0.4199	Yes
29	KLHL13	3181	1.378	0.4272	Yes
30	GSK3B	3225	1.361	0.4361	Yes
31	RACGAP1	3251	1.348	0.4459	Yes
32	TNF	3329	1.321	0.4527	Yes
33	MAP3K14	3357	1.311	0.4620	Yes
34	INCENP	3407	1.289	0.4700	Yes
35	TACC3	3437	1.278	0.4790	Yes
36	TDRD7	3548	1.233	0.4833	Yes
37	AURKA	3558	1.229	0.4929	Yes
38	PPP1CC	3973	1.074	0.4795	No
39	TNFRSF1A	4410	0.935	0.4636	No
40	BIRC5	4482	0.913	0.4674	No
41	ATM	4489	0.911	0.4746	No
42	CENPA	4741	0.829	0.4679	No
43	STMN1	4884	0.793	0.4667	No
44	BCL10	5071	0.732	0.4627	No
45	RAN	5137	0.712	0.4651	No
46	CPEB1	5309	0.664	0.4614	No
47	RHOA	5418	0.627	0.4607	No
48	AURKB	5442	0.622	0.4646	No
49	JUB	5576	0.585	0.4623	No
50	SRC	5891	0.502	0.4495	No
51	EVI5	6013	0.474	0.4469	No
52	RELA	6756	0.290	0.4092	No
53	AKT1	7193	0.191	0.3873	No
54	KIF2C	7420	0.138	0.3762	No
55	PAK1	7492	0.119	0.3734	No
56	XPO1	7732	0.068	0.3610	No
57	FBXW11	7737	0.066	0.3614	No
58	BUB1	8427	-0.087	0.3249	No
59	PRKCA	8787	-0.161	0.3069	No
60	TP53	9109	-0.232	0.2914	No
61	TNFAIP3	9114	-0.232	0.2932	No
62	PIK3R1	9905	-0.397	0.2538	No
63	NPM1	10521	-0.513	0.2248	No
64	OAZ1	10864	-0.575	0.2111	No
65	BRCA1	10914	-0.586	0.2133	No
66	DES	10986	-0.600	0.2145	No
67	NFKB1	11045	-0.612	0.2164	No
68	CDCA8	11521	-0.699	0.1965	No
69	SYK	11805	-0.741	0.1874	No
70	KIF20A	12225	-0.822	0.1716	No
71	GADD45A	12625	-0.894	0.1574	No
72	NFKBIA	12659	-0.899	0.1630	No
73	ERC1	12967	-0.957	0.1544	No
74	AURKC	13021	-0.965	0.1595	No
75	LCK	13229	-1.005	0.1566	No
76	MYLK	14075	-1.166	0.1207	No
77	ARHGEF7	14194	-1.194	0.1241	No
78	PRKACA	14249	-1.207	0.1312	No
79	VIM	14259	-1.209	0.1407	No
80	NFKB2	14726	-1.307	0.1263	No
81	CDC25B	15829	-1.580	0.0799	No
82	RELB	16217	-1.686	0.0730	No
83	PPP2R5D	16504	-1.784	0.0723	No
84	CBX5	17258	-2.087	0.0489	No
85	ARRB2	18269	-2.950	0.0187	No